COVID-19 Outpatient Treatment

Monoclonal Antibody Infusions for mild COVID-19

Community Hospital has a limited supply of monoclonal antibody infusions that have been given Emergency Authorization by the Federal Drug Administration (FDA) for treatment of mild (or early stage) COVID-19 in certain high-risk patients who do not require hospital admission for their COVID symptoms. The antibodies are given as a one-time intravenous infusion. There are two products currently being administered. Either REGEN-COV (casirivimab/imdevimab), or Sotrovimab, may be given depending on current supplies.

Frequently asked questions

What are monoclonal antibodies?

Antibodies are proteins that people's bodies make to fight viruses, such as the virus that causes COVID-19. Antibodies made in a laboratory act like natural antibodies to limit the amount of virus in your body. Laboratory and synthetically produced antibodies are called monoclonal antibodies.

Should I consider getting monoclonal antibody treatment?

Research studies have shown that infusion of monoclonal antibodies in the early stages of COVID-19 infection can decrease the chance that people with risk factors for severe disease will get worse, and decrease the chance that they would need to return to the Emergency Department, or be admitted to the hospital for COVID-19 symptoms.

When should I get monoclonal antibody treatment?

Monoclonal antibody treatment is time-sensitive, and must be given soon after a COVID-19 diagnosis is made. It is most effective when given early, and cannot be given if symptoms have been present for 10 days or more.

How do I get monoclonal antibody treatment?

If you were seen at Community Hospital’s Emergency department, staff will contact you by phone if you are eligible. You may also reply through MyChart messaging if you are interested, and someone will contact you by phone with next steps to schedule an infusion appointment. If you received a positive test and think you are eligible, please contact your local doctor so that they can determine your eligibility for treatment.

How long does monoclonal antibody treatment take?

Treatment could take as little as 2 hours or less, but can vary due to other factors.

If I have been vaccinated, can I still use this treatment?

Being fully vaccinated against COVID-19 is not an absolute contraindication to treatment, but there is no evidence to support benefit of monoclonal antibody treatment for breakthrough infection in someone with pre-existing vaccine-induced immunity. Consideration may be given to treating a fully vaccinated person if there is evidence of suboptimal response to vaccination such as a negative COVID-19 serology or an immunosuppressed state that would have precluded development of an adequate vaccine response (e.g. prior treatment with rituximab).

What if I am pregnant or breastfeeding?

There is limited experience using REGEN-COV (casirivimab and imdevimab) and Sotrovimab in pregnant women or breastfeeding mothers. For a mother and unborn baby, the benefit of receiving REGEN-COV (casirivimab and imdevimab) and Sotrovimab may be greater than the risk of using the product. If you are pregnant or breastfeeding, discuss your options and specific situation with your healthcare provider.

Where can I go to find more information about monoclonal antibody treatment?

Visit our Coronavirus Information page to learn more about COVID-19 testing locations, vaccines and more.